Pre-cancerous

Erythroplasia

Also known as: Erythroplakia

Bright red velvety plaque in the mouth. Over 50% harbor cancer at diagnosis - the most dangerous oral precancer.

What to look for

Side-by-side comparison

Normal mouth

Pink, healthy mucosa

Erythroplasia

Bright red velvety patch

Erythroplasia appears as a bright red, velvety, well-defined patch on oral mucous membranes. Unlike leukoplakia's white patches, erythroplasia is red - and far more dangerous.

At biopsy, over 50% already contain carcinoma in situ or invasive SCC, and approximately 90% show at least severe dysplasia. This makes erythroplasia a much higher-risk finding than leukoplakia.

Most common in men aged 50-70 with tobacco and alcohol use. Any persistent red mouth patch lasting over two weeks requires urgent evaluation.

Quick self-check

Does this look like erythroplasia? Answer 2 questions.

Is there a persistent red, velvety patch inside your mouth?

Has it been there more than two weeks?

Risk factors

  • Tobacco use
  • Heavy alcohol (especially with tobacco)
  • Age 50-70
  • Male sex
  • Betel nut chewing

When to see a dermatologist

  • Any persistent red mouth patch lasting more than two weeks - URGENT
  • A velvety red area on tongue, floor of mouth, or palate
  • Mixed red and white mouth patches

Often confused with

Not sure if this is erythroplasia? Compare:

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Frequently asked questions

Why is erythroplasia more dangerous than leukoplakia?

Leukoplakia has 3-17% malignant transformation rate. Erythroplasia already contains carcinoma in over 50% of cases at biopsy. A red mouth patch is far more urgent than a white one.

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